Does inhibition of angiotensin function cause neuroprotection in diffuse traumatic brain injury?

Does inhibition of angiotensin function cause neuroprotection in diffuse traumatic brain injury?

Objective(s): Neuroprotection is created following the inhibition of angiotensin II type 1 receptor (AT1R). Therefore, the purpose of this research was examining AT1R blockage by candesartan in diffuse traumatic brain injury (TBI). Materials and Methods: Male rats were assigned into sham, TBI, vehic...

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Bibliographic Details
Main Authors: Mohammad Khaksari, Mohammad Amin Rajizadeh, Mohammad Abbas Bejeshk, Zahra Soltani, Sina Motamedi, Fatemeh Moramdi, Masoud Islami, Shahriyar Shafa, Sepehr Khosravi
Format: Article
Language:English
Published: Mashhad University of Medical Sciences 2018-06-01
Series:Iranian Journal of Basic Medical Sciences
Subjects:
Angiotensin II receptor
Blood-brain barrier
Brain edema
Brain injury
Candesartan
Intracranial pressure
Lipid peroxidation
Online Access:http://ijbms.mums.ac.ir/article_10694_0a2ad7a22d187d10470a8d705e98ff92.pdf

Internet

http://ijbms.mums.ac.ir/article_10694_0a2ad7a22d187d10470a8d705e98ff92.pdf

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