NS2B/NS3 mutations enhance the infectivity of genotype I Japanese encephalitis virus in amplifying hosts.

NS2B/NS3 mutations enhance the infectivity of genotype I Japanese encephalitis virus in amplifying hosts.

Genotype I (GI) virus has replaced genotype III (GIII) virus as the dominant Japanese encephalitis virus (JEV) in the epidemic area of Asia. The mechanism underlying the genotype replacement remains unclear. Therefore, we focused our current study on investigating the roles of mosquito vector and am...

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Bibliographic Details
Main Authors: Yi-Chin Fan, Jian-Jong Liang, Jo-Mei Chen, Jen-Wei Lin, Yi-Ying Chen, Kuan-Hsuan Su, Chang-Chi Lin, Wu-Chun Tu, Ming-Tang Chiou, Shan-Chia Ou, Gwong-Jen J Chang, Yi-Ling Lin, Shyan-Song Chiou
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-08-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1007992

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https://doi.org/10.1371/journal.ppat.1007992

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