RASopathic skin eruptions during vemurafenib therapy.

Vemurafenib is a potent inhibitor of V600 mutant BRAF with significant impact on progression-free and overall survival in advanced melanoma. Cutaneous side effects are frequent. This single-center observational study investigates clinical and histological features of these class-specific cutaneous a...

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Bibliographic Details
Main Authors: Jeannine D Rinderknecht, Simone M Goldinger, Sima Rozati, Jivko Kamarashev, Katrin Kerl, Lars E French, Reinhard Dummer, Benedetta Belloni
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3597638?pdf=render