Decreased DNA methylation of a CpG site in the HBAP1 gene in plasma DNA from pregnant women.

OBJECTIVE:The objective of this study is to identify potential CpG site(s) or DNA methylation pattern(s) in the pseudo α-globin 1 gene (HBAP1 gene), the gene which locates in α-thalassemia-1 deletion mutation, to differentiate plasma DNA between pregnant and non-pregnant women. METHOD:DNA methylatio...

Full description

Bibliographic Details
Main Authors: Tanapat Pangeson, Torpong Sanguansermsri, Khwanruedee Mahingsa, Phanchana Sanguansermsri
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5967787?pdf=render