Individual liver plasmacytoid dendritic cells are capable of producing IFNα and multiple additional cytokines during chronic HCV infection.

Individual liver plasmacytoid dendritic cells are capable of producing IFNα and multiple additional cytokines during chronic HCV infection.

Plasmacytoid dendritic cells (pDCs) are "natural" interferon α (IFNα)-producing cells. Despite their importance to antiviral defense, autoimmunity, and ischemic liver graft injury, because DC subsets are rare and heterogeneous, basic questions about liver pDC function and capacity to make...

Full description

Bibliographic Details
Main Authors: Erin Heather Doyle, Adeeb Rahman, Costica Aloman, Arielle L Klepper, Ahmed El-Shamy, Francis Eng, Chiara Rocha, Sang Kim, Brandy Haydel, Sander S Florman, M Isabel Fiel, Thomas Schiano, Andrea D Branch
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-07-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1007935

Internet

https://doi.org/10.1371/journal.ppat.1007935

Similar Items