Gambogic Acid Lysinate Induces Apoptosis in Breast Cancer MCF-7 Cells by Increasing Reactive Oxygen Species

Gambogic acid (GA) inhibits the proliferation of various human cancer cells. However, because of its water insolubility, the antitumor efficacy of GA is limited. Objectives. To investigate the antitumor activity of gambogic acid lysinate (GAL) and its mechanism. Methods. Inhibition of cell prolifera...

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Bibliographic Details
Main Authors: Yong-Zhan Zhen, Ya-Jun Lin, Kai-Ji Li, Xiao-Shan Yang, Yu-Fang Zhao, Jie Wei, Jing-Bo Wei, Gang Hu
Format: Article
Language:English
Published: Hindawi Limited 2015-01-01
Series:Evidence-Based Complementary and Alternative Medicine
Online Access:http://dx.doi.org/10.1155/2015/842091