MutScan: fast detection and visualization of target mutations by scanning FASTQ data
Abstract Background Some types of clinical genetic tests, such as cancer testing using circulating tumor DNA (ctDNA), require sensitive detection of known target mutations. However, conventional next-generation sequencing (NGS) data analysis pipelines typically involve different steps of filtering,...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2018-01-01
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Series: | BMC Bioinformatics |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12859-018-2024-6 |