Analysis of loss of heterozygosity of the tumor suppressor genes p53 and BRCA1 in ovarial carcinomas

Analysis of loss of heterozygosity of the tumor suppressor genes p53 and BRCA1 in ovarial carcinomas

Background/aim: Among the genes involved in ovarian carcinogenesis, there has been increased interest in tumor-suppressor genes p53 and BRCA1. Both of the genes make control of cell cycle, DNA repair and apoptosis. The p53 is a "genome guardian" inactivated in more than 50% of human cancer...

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Bibliographic Details
Main Authors: Luković Ljiljana, Popović Branka, Atanacković Jasmina, Novaković Ivana, Perović Milica, Petrović Bojana, Petković Spasoje
Format: Article
Language:English
Published: Military Health Department, Ministry of Defance, Serbia 2006-01-01
Series:Vojnosanitetski Pregled
Subjects:
ovarian neoplasms
loss of heterozygosity
genes
p53
BRCA1
Online Access:http://www.doiserbia.nb.rs/img/doi/0042-8450/2006/0042-84500609813P.pdf

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http://www.doiserbia.nb.rs/img/doi/0042-8450/2006/0042-84500609813P.pdf

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