Insights from pharmacokinetic models of host-microbiome drug metabolism

Increasing evidence suggests a role of the gut microbiota in patients’ response to medicinal drugs. In our recent study, we combined genomics of human gut commensals and gnotobiotic animal experiments to quantify microbiota and host contributions to drug metabolism. Informed by experimental data, we...

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Bibliographic Details
Main Authors: Maria Zimmermann-Kogadeeva, Michael Zimmermann, Andrew L. Goodman
Format: Article
Language:English
Published: Taylor & Francis Group 2020-05-01
Series:Gut Microbes
Subjects:
Online Access:http://dx.doi.org/10.1080/19490976.2019.1667724