Impact of the detection of ζ-globin chains and hemoglobin Bart's using immunochromatographic strip tests for α0-thalassemia (--SEA) differential diagnosis.

α0-Thalassemia is an inherited hematological disorder caused by the deletion of α-globin genes. The Southeast Asian deletion (--SEA) is the most common type of α0-thalassemia observed in Southeast Asian countries. Regarding WHO health policy, an effective α0-thalassemia screening strategy is needed...

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Main Authors: Supansa Pata, Witida Laopajon, Matawee Pongpaiboon, Weeraya Thongkum, Nattapong Polpong, Thongperm Munkongdee, Kittiphong Paiboonsukwong, Suthat Fucharoen, Chatchai Tayapiwatana, Watchara Kasinrerk
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0223996