Network Analysis Identifies Crosstalk Interactions Governing TGF-β Signaling Dynamics during Endoderm Differentiation of Human Embryonic Stem Cells

Network Analysis Identifies Crosstalk Interactions Governing TGF-β Signaling Dynamics during Endoderm Differentiation of Human Embryonic Stem Cells

The fate choice of human embryonic stem cells (hESCs) is controlled by complex signaling milieu synthesized by diverse chemical factors in the growth media. Prevalence of crosstalks and interactions between parallel pathways renders any analysis probing the process of fate transition of hESCs elusiv...

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Bibliographic Details
Main Authors: Shibin Mathew, Sankaramanivel Sundararaj, Ipsita Banerjee
Format: Article
Language:English
Published: MDPI AG 2015-05-01
Series:Processes
Subjects:
dynamic bayesian networks
endoderm
human embryonic stem cells
network inference
signaling crosstalks
Online Access:http://www.mdpi.com/2227-9717/3/2/286

Internet

http://www.mdpi.com/2227-9717/3/2/286

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