Adipocyte-derived IL-6 and leptin promote breast Cancer metastasis via upregulation of Lysyl Hydroxylase-2 expression

Adipocyte-derived IL-6 and leptin promote breast Cancer metastasis via upregulation of Lysyl Hydroxylase-2 expression

Abstract Background Adipocytes make up the major component of breast tissue, accounting for 90% of stromal tissue. Thus, the crosstalk between adipocytes and breast cancer cells may play a critical role in cancer progression. Adipocyte-breast cancer interactions have been considered important for th...

Full description

Bibliographic Details
Main Authors: Jin-Yong He, Xiao-Hui Wei, Si-Jing Li, Yang Liu, Hao-Lin Hu, Zheng-Zheng Li, Xin-Hong Kuang, Lai Wang, Xin Shi, Sheng-Tao Yuan, Li Sun
Format: Article
Language:English
Published: BMC 2018-12-01
Series:Cell Communication and Signaling
Subjects:
Adipocytes
PLOD2
IL-6
Leptin
Breast Cancer
Metastasis
Online Access:http://link.springer.com/article/10.1186/s12964-018-0309-z

Internet

http://link.springer.com/article/10.1186/s12964-018-0309-z

Similar Items