Interference with the Cannabinoid Receptor CB1R Results in Miswiring of GnRH3 and AgRP1 Axons in Zebrafish Embryos

Interference with the Cannabinoid Receptor CB1R Results in Miswiring of GnRH3 and AgRP1 Axons in Zebrafish Embryos

The G protein-coupled cannabinoid receptors type 1 (CB1R) and type 2 (CB2R), and their endocannabinoid (eCBs) ligands, have been implicated in several aspects of brain wiring during development. Here we aim to assess whether interfering with CB1R affects development, neuritogenesis and pathfinding o...

Full description

Bibliographic Details
Main Authors: Giulia Zuccarini, Ilaria D’Atri, Erika Cottone, Ken Mackie, Inbal Shainer, Yoav Gothilf, Paolo Provero, Patrizia Bovolin, Giorgio Roberto Merlo
Format: Article
Language:English
Published: MDPI AG 2019-12-01
Series:International Journal of Molecular Sciences
Subjects:
cannabinoid receptor
gnrh
agrp
neuroendocrine
axon guidance
stathmin
zebrafish
Online Access:https://www.mdpi.com/1422-0067/21/1/168

Internet

https://www.mdpi.com/1422-0067/21/1/168

Similar Items