Genome-wide DNA Methylation Profiling of Cell-Free Serum DNA in Esophageal Adenocarcinoma and Barrett Esophagus

Aberrant DNA methylation (DNAm) is a feature of most types of cancers. Genome-wide DNAm profiling has been performed successfully on tumor tissue DNA samples. However, the invasive procedure limits the utility of tumor tissue for epidemiological studies. While recent data indicate that cell-free ci...

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Bibliographic Details
Main Authors: Rihong Zhai, Yang Zhao, Li Su, Lauren Cassidy, Geoffrey Liu, David C. Christiani
Format: Article
Language:English
Published: Elsevier 2012-01-01
Series:Neoplasia: An International Journal for Oncology Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558612800753