High-content, image-based screening for drug targets in yeast.

BACKGROUND: Drug discovery and development are predicated on elucidation of the potential mechanisms of action and cellular targets of candidate chemical compounds. Recent advances in high-content imaging techniques allow simultaneous analysis of a range of cellular events. In this study, we propose...

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Bibliographic Details
Main Authors: Shinsuke Ohnuki, Satomi Oka, Satoru Nogami, Yoshikazu Ohya
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2854693?pdf=render