Alginate Microencapsulation of Human Islets Does Not Increase Susceptibility to Acute Hypoxia

Islet transplantation in diabetes is hampered by the need of life-long immunosuppression. Encapsulation provides partial immunoprotection but could possibly limit oxygen supply, a factor that may enhance hypoxia-induced beta cell death in the early posttransplantation period. Here we tested suscepti...

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Bibliographic Details
Main Authors: I. K. Hals, A. M. Rokstad, B. L. Strand, J. Oberholzer, V. Grill
Format: Article
Language:English
Published: Hindawi Limited 2013-01-01
Series:Journal of Diabetes Research
Online Access:http://dx.doi.org/10.1155/2013/374925