Evaluation of the Predictive Performance of Population Pharmacokinetic Models of Adalimumab in Patients with Inflammatory Bowel Disease

Adalimumab is a monoclonal antibody used for inflammatory bowel disease. Due to its considerably variable pharmacokinetics, the loss of response and the development of anti-antibodies, it is highly recommended to use a model-informed precision dosing approach. The aim of this study is to evaluate th...

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Bibliographic Details
Main Authors: Silvia Marquez-Megias, Amelia Ramon-Lopez, Patricio Más-Serrano, Marcos Diaz-Gonzalez, Maria Remedios Candela-Boix, Ricardo Nalda-Molina
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Pharmaceutics
Subjects:
Online Access:https://www.mdpi.com/1999-4923/13/8/1244