Cytochrome c as a potentially clinical useful marker of mitochondrial and cellular damage
Mitochondria are evolutionary endosymbionts derived from bacteria. Thus they bear molecules, such as mitochondrial DNA that contains CpG DNA repeats and N-formyl peptides, found in bacteria. Upon cell necrosis or apoptosis these molecules are released into the interstitial space and the circulation...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2016-07-01
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Series: | Frontiers in Immunology |
Subjects: | |
Online Access: | http://journal.frontiersin.org/Journal/10.3389/fimmu.2016.00279/full |