Thioredoxin Confers Intrinsic Resistance to Cytostatic Drugs in Human Glioma Cells

Thioredoxin (Trx) overexpression is known to be a cause of chemotherapy resistance in various tumor entities. However, Trx effects on resistance are complex and depend strictly on tissue type. In the present study, we analyzed the impact of the Trx system on intrinsic chemoresistance of human gliobl...

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Bibliographic Details
Main Authors: Bodo Haas, Lena Schütte, Maria Wos-Maganga, Sandra Weickhardt, Marco Timmer, Niels Eckstein
Format: Article
Language:English
Published: MDPI AG 2018-09-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:http://www.mdpi.com/1422-0067/19/10/2874