Plasma sphingosine-1-phosphate is elevated in obesity.

BACKGROUND: Dysfunctional lipid metabolism is a hallmark of obesity and insulin resistance and a risk factor for various cardiovascular and metabolic complications. In addition to the well known increase in plasma triglycerides and free fatty acids, recent work in humans and rodents has shown that o...

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Bibliographic Details
Main Authors: Greg M Kowalski, Andrew L Carey, Ahrathy Selathurai, Bronwyn A Kingwell, Clinton R Bruce
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3765451?pdf=render