Identification of Androgen Receptor Metabolic Correlome Reveals the Repression of Ceramide Kinase by Androgens

Identification of Androgen Receptor Metabolic Correlome Reveals the Repression of Ceramide Kinase by Androgens

Prostate cancer (PCa) is one of the most prevalent cancers in men. Androgen receptor signaling plays a major role in this disease, and androgen deprivation therapy is a common therapeutic strategy in recurrent disease. Sphingolipid metabolism plays a central role in cell death, survival, and therapy...

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Bibliographic Details
Main Authors: Laura Camacho, Amaia Zabala-Letona, Ana R. Cortazar, Ianire Astobiza, Asier Dominguez-Herrera, Amaia Ercilla, Jana Crespo, Cristina Viera, Sonia Fernández-Ruiz, Ainara Martinez-Gonzalez, Veronica Torrano, Natalia Martín-Martín, Antonio Gomez-Muñoz, Arkaitz Carracedo
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Cancers
Subjects:
prostate cancer
bioinformatics
mouse models
sphingolipid metabolism
ceramide kinase
Online Access:https://www.mdpi.com/2072-6694/13/17/4307

Internet

https://www.mdpi.com/2072-6694/13/17/4307

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