Electrosprayed Alginate Nanoparticles as CRISPR Plasmid DNA Delivery Carrier: Preparation, Optimization, and Characterization

Therapeutic gene editing is becoming more feasible with the emergence of the Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)/CRISPR-associated protein (Cas) system. However, the successful implementation of CRISPR/Cas9-based therapeutics requires a safe and efficient in vivo deliv...

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Bibliographic Details
Main Authors: Batoul Alallam, Sara Altahhan, Muhammad Taher, Mohd Hamzah Mohd Nasir, Abd Almonem Doolaanea
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Pharmaceuticals
Subjects:
Online Access:https://www.mdpi.com/1424-8247/13/8/158