Engineering of Botulinum Neurotoxins for Biomedical Applications
Botulinum neurotoxins (BoNTs) have been used as therapeutic agents in the clinical treatment of a wide array of neuromuscular and autonomic neuronal transmission disorders. These toxins contain three functional domains that mediate highly specific neuronal cell binding, internalization and cytosolic...
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Format: | Article |
Language: | English |
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MDPI AG
2018-06-01
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Series: | Toxins |
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Online Access: | http://www.mdpi.com/2072-6651/10/6/231 |