Is the History Repeated? Can (2,6)-Hydroxynorketamine be Another Antidepressant?

Historically, identification of active metabolites has contributed to drug discovery for psychiatric disorders. It has led to the identification of new medications such as desipramine (a metabolite of imipramine) and paliperidone (a metabolite of risperidone). ( R,S )-Ketamine, which has been regard...

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Bibliographic Details
Main Authors: Shigeyuki Chaki, Jun-ichi Yamaguchi
Format: Article
Language:English
Published: SAGE Publishing 2018-12-01
Series:Journal of Experimental Neuroscience
Online Access:https://doi.org/10.1177/1179069518815445