ApoB100/LDLR-/- hypercholesterolaemic mice as a model for mild cognitive impairment and neuronal damage.

Recent clinical findings support the notion that the progressive deterioration of cholesterol homeostasis is a central player in Alzheimer's disease (AD). Epidemiological studies suggest that high midlife plasma total cholesterol levels are associated with an increased risk of AD. This paper re...

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Bibliographic Details
Main Authors: Carlos Ramírez, Saleta Sierra, Inmaculada Tercero, Jose Antonio Vázquez, Antonia Pineda, Tatiana Manrique, Javier S Burgos
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3144244?pdf=render