Circulating Tumor DNA Analyses Predict Disease Recurrence in Non-Muscle-Invasive Bladder Cancer

Circulating Tumor DNA Analyses Predict Disease Recurrence in Non-Muscle-Invasive Bladder Cancer

Circulating tumor DNA (ctDNA) can be a prognostic biomarker for non-muscle-invasive bladder cancer (NMIBC); however, targeted sequencing has not been performed to detect ctDNA in NMIBC. We applied targeted sequencing based on an 861-gene panel to determine mutations in tumor tissue DNA and plasma ct...

Full description

Bibliographic Details
Main Authors: Jinghua Zhang, Daofeng Dai, Junqiang Tian, Lifeng Li, Jing Bai, Yaping Xu, Zhiping Wang, Aifa Tang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Oncology
Subjects:
non-muscle-invasive bladder cancer
circulating tumor DNA
targeted sequencing
prognostic biomarker
chemotherapy
molecular tumor burden index
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.657483/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2021.657483/full

Similar Items