Cellular stress-induced up-regulation of FMRP promotes cell survival by modulating PI3K-Akt phosphorylation cascades

<p>Abstract</p> <p>Background</p> <p>Fragile X syndrome (FXS), the most commonly inherited mental retardation and single gene cause of autistic spectrum disorder, occurs when the Fmr1 gene is mutated. The product of Fmr1, fragile X linked mental retardation protein (FMR...

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Bibliographic Details
Main Authors: Wells David, Choi Ji, Yang Sung-Il, Seo Jung, Jeon Se, Shin Chan, Ko Kwang
Format: Article
Language:English
Published: BMC 2011-02-01
Series:Journal of Biomedical Science
Online Access:http://www.jbiomedsci.com/content/18/1/17