Cellular stress-induced up-regulation of FMRP promotes cell survival by modulating PI3K-Akt phosphorylation cascades
<p>Abstract</p> <p>Background</p> <p>Fragile X syndrome (FXS), the most commonly inherited mental retardation and single gene cause of autistic spectrum disorder, occurs when the Fmr1 gene is mutated. The product of Fmr1, fragile X linked mental retardation protein (FMR...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2011-02-01
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Series: | Journal of Biomedical Science |
Online Access: | http://www.jbiomedsci.com/content/18/1/17 |