COX-2 activation is associated with Akt phosphorylation and poor survival in ER-negative, HER2-positive breast cancer

<p>Abstract</p> <p>Background</p> <p>Inducible cyclooxgenase-2 (COX-2) is commonly overexpressed in breast tumors and is a target for cancer therapy. Here, we studied the association of COX-2 with breast cancer survival and how this association is influenced by tumor es...

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Bibliographic Details
Main Authors: Goodman Julie E, Wink David A, Dorsey Tiffany M, Boersma Brenda J, Ridnour Lisa A, Prueitt Robyn L, Glynn Sharon A, Yfantis Harris G, Lee Dong H, Ambs Stefan
Format: Article
Language:English
Published: BMC 2010-11-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/10/626