Shaping of CD56bri Natural Killer Cells in Patients With Steroid-Refractory/Resistant Acute Graft-vs.-Host Disease via Extracorporeal Photopheresis

Shaping of CD56bri Natural Killer Cells in Patients With Steroid-Refractory/Resistant Acute Graft-vs.-Host Disease via Extracorporeal Photopheresis

CD56bri natural killer (NK) cells play an important role in the pathogenesis of graft-vs. -host disease (GVHD) and immune defense in the early period after allogeneic hematopoietic stem cell transplantation. Extracorporeal photopheresis (ECP) as an immunomodulating therapy has been widely used for G...

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Bibliographic Details
Main Authors: Ming Ni, Lei Wang, Mingya Yang, Brigitte Neuber, Leopold Sellner, Angela Hückelhoven-Krauss, Maria-Luisa Schubert, Thomas Luft, Ute Hegenbart, Stefan Schönland, Patrick Wuchter, Bao-an Chen, Volker Eckstein, William Krüger, Ronit Yerushalmi, Katia Beider, Arnon Nagler, Carsten Müller-Tidow, Peter Dreger, Michael Schmitt, Anita Schmitt
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-03-01
Series:Frontiers in Immunology
Subjects:
GvHD
ECP
immunomodulation
natural killer cells
anti-viral effect
anti-leukemia effect
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.00547/full

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https://www.frontiersin.org/article/10.3389/fimmu.2019.00547/full

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