Hyperbaric Oxygen Inhibits Reperfusion-Induced Neutrophil Polarization and Adhesion Via Plasmin-Mediated VEGF Release

Background:. Ischemia-reperfusion (IR) injury is seen in many settings such as free flap salvage and limb replantation/revascularization. The consequences—partial/total flap loss, functional muscle loss, or amputation—can be devastating. Of the treatment options available for IR injury, hyperbaric o...

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Main Authors: Ashish Francis, MD, Shawna R. Kleban, MD, Linda L. Stephenson, BS, Patrick S. Murphy, MD, Peter R. Letourneau, MD, Xin-Hua Fang, MT, Wei Z. Wang, MD, Richard C. Baynosa, MD
Format: Article
Language:English
Published: Wolters Kluwer 2017-09-01
Series:Plastic and Reconstructive Surgery, Global Open
Online Access:http://journals.lww.com/prsgo/fulltext/10.1097/GOX.0000000000001497