Validation of a modified fluorimetric assay for the screening of trichomonacidal drugs

A fluorimetric microassay that uses a redox dye to determine the viability of the flagellate Trichomonas vaginalis has been optimised to provide a more sensitive method to evaluate potential trichomonacidal compounds. Resazurin has been used in recent years to test drugs against different parasites,...

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Bibliographic Details
Main Authors: Alexandra Ibáñez Escribano, Alfredo Meneses Marcel, Yanetsy Machado Tugores, Juan José Nogal Ruiz, Vicente J Arán Redó, José Antonio Escario García-Trevijano, Alicia Gómez Barrio
Format: Article
Language:English
Published: Instituto Oswaldo Cruz, Ministério da Saúde 2012-08-01
Series:Memórias do Instituto Oswaldo Cruz.
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762012000500010&lng=en&tlng=en