Alternative kynurenic acid synthesis routes studied in the rat cerebellum

Alternative kynurenic acid synthesis routes studied in the rat cerebellum

Kynurenic acid (KYNA), an astrocyte-derived, endogenous antagonist of α7 nicotinic acetylcholine and excitatory amino acid receptors, regulates glutamatergic, GABAergic, cholinergic and dopaminergic neurotransmission in several regions of the rodent brain. Synthesis of KYNA in the brain and elsewher...

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Bibliographic Details
Main Authors: Tonali eBlanco Ayala, Rafael eLugo Huitrón, Liliana eAparicio Carmona, Daniela eRamirez Ortega, Dinora eGonzalez Esquivel, José ePedraza Chaverrí, Gonzalo ePérez de la Cruz, Camilo eRios, Robert eSchwarcz, Verónica ePérez de la Cruz
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-05-01
Series:Frontiers in Cellular Neuroscience
Subjects:
Kynurenine
Microdialysis
Oxidative Stress
Reactive Oxygen Species
D-amino acid oxidase
Online Access:http://journal.frontiersin.org/Journal/10.3389/fncel.2015.00178/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fncel.2015.00178/full

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