Regulation and novel action of thymidine phosphorylase in non-small cell lung cancer: crosstalk with Nrf2 and HO-1.

Regulation and novel action of thymidine phosphorylase in non-small cell lung cancer: crosstalk with Nrf2 and HO-1.

Proangiogenic enzyme thymidine phosphorylase (TP) is a promising target for anticancer therapy, yet its action in non-small cell lung carcinoma (NSCLC) is not fully understood. To elucidate its role in NSCLC tumor growth, NCI-H292 lung mucoepidermoid carcinoma cells and endothelial cells were engine...

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Bibliographic Details
Main Authors: Magdalena Tertil, Klaudia Skrzypek, Urszula Florczyk, Kazimierz Weglarczyk, Halina Was, Guillaume Collet, Alan Guichard, Tomasz Gil, Jaroslaw Kuzdzal, Alicja Jozkowicz, Claudine Kieda, Chantal Pichon, Jozef Dulak
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4018251?pdf=render

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http://europepmc.org/articles/PMC4018251?pdf=render

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