Monoclonal Antibody 16D10 to the C-Terminal Domain of the Feto-Acinar Pancreatic Protein Binds to Membrane of Human Pancreatic Tumoral SOJ-6 Cells and Inhibits the Growth of Tumor Xenografts

Monoclonal Antibody 16D10 to the C-Terminal Domain of the Feto-Acinar Pancreatic Protein Binds to Membrane of Human Pancreatic Tumoral SOJ-6 Cells and Inhibits the Growth of Tumor Xenografts

Feto-acinar pancreatic protein (FAPP) characterized by mAbJ28 reactivity is a specific component associated with ontogenesis and behaves as an oncodevelopment-associated antigen. We attempted to determine whether pancreatic tumoral SOJ-6 cells are expressed at their surface FAPP antigens and to exa...

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Bibliographic Details
Main Authors: Laurence Panicot-Dubois, Muriel Aubert, Cécile Franceschi, Eric Mas, Françoise Silvy, Christian Crotte, Jean-Paul Bernard, Dominique Lombardo, Marie-Odile Sadoulet
Format: Article
Language:English
Published: Elsevier 2004-11-01
Series:Neoplasia: An International Journal for Oncology Research
Subjects:
Pancreas
cancer
bile salt-dependent lipase (BSDL)
feto-acinar pancreatic protein (FAPP)
monoclonal antibody
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558604800034

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http://www.sciencedirect.com/science/article/pii/S1476558604800034

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