Mesenchymal stem cell-mediated delivery of therapeutic adenoviral vectors to prostate cancer

Abstract Background There is an urgent need for targeted biological therapies for prostate cancer with greater efficacy and less toxicity, particularly for metastatic disease, where current therapies are not curative. Therapeutic adenoviral vectors or oncolytic adenoviruses offer the possibility of...

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Bibliographic Details
Main Authors: Tahir Muhammad, Ali Sakhawat, Aamir Ali Khan, Ling Ma, Ruth A. Gjerset, Yinghui Huang
Format: Article
Language:English
Published: BMC 2019-06-01
Series:Stem Cell Research & Therapy
Subjects:
p53
Online Access:http://link.springer.com/article/10.1186/s13287-019-1268-z