Rational in silico drug design of HIV-RT inhibitors through G-QSAR and molecular docking study of 4-arylthio and 4-aryloxy-3-iodopyridine-2(1-H)-one derivative

Rational in silico drug design of HIV-RT inhibitors through G-QSAR and molecular docking study of 4-arylthio and 4-aryloxy-3-iodopyridine-2(1-H)-one derivative

Abstract Background Human immunodeficiency virus infection and acquired immune deficiency syndrome (HIV/AIDS) is a spectrum of conditions caused by infection with the human immunodeficiency virus (HIV). Antiretroviral therapy (ART) against HIV infection offers the promise of controlling disease prog...

Full description

Bibliographic Details
Main Authors: Debadash Panigrahi, Amiyakanta Mishra, Susanta Kumar Sahu
Format: Article
Language:English
Published: SpringerOpen 2020-11-01
Series:Beni-Suef University Journal of Basic and Applied Sciences
Subjects:
Quantitative structure activity relationship
G-QSAR
Antiretroviral therapy (ART)
Anti-HIV
Reverse transcriptase inhibitor
Molecular docking
Online Access:https://doi.org/10.1186/s43088-020-00075-7

Internet

https://doi.org/10.1186/s43088-020-00075-7

Similar Items