Establishment of a novel mesenchymal stem cell-based regimen for chronic myeloid leukemia differentiation therapy

Abstract Chronic myeloid leukemia (CML) is characterized by the accumulation of malignant and immature white blood cells which spread to the peripheral blood and other tissues/organs. Despite the fact that current tyrosine kinase inhibitors (TKIs) are capable of achieving the complete remission by r...

Full description

Bibliographic Details
Main Authors: Shiman Zuo, Luchen Sun, Yuxin Wang, Bing Chen, Jingyue Wang, Xiangyu Ge, Yan Lu, Nanfei Yang, Pingping Shen
Format: Article
Language:English
Published: Nature Publishing Group 2021-02-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-021-03499-w