Mechanisms of Primary and Secondary Resistance to Immune Checkpoint Inhibitors in Cancer

Immune checkpoint inhibitors (ICPis) have revolutionized cancer therapy with broad activities against a wide range of malignancies. However, in many malignancies their efficacy remains limited due to the primary resistance. Furthermore, a high percentage of patients develop progression due to the se...

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Bibliographic Details
Main Authors: Tiffany Seto, Danny Sam, Minggui Pan
Format: Article
Language:English
Published: MDPI AG 2019-01-01
Series:Medical Sciences
Subjects:
PD1
TCR
Online Access:https://www.mdpi.com/2076-3271/7/2/14