A metaphyseal fracture rat model for mechanistic studies of osteoporotic bone healing

Most osteoporotic fractures occur at metaphyseal regions of long bones. The present study proposed a clinically relevant animal model that satisfied: i) induction of osteoporosis, ii) unilateral complete osteotomy at metaphysis, iii) internal fixation. 6 months old female Sprague-Dawley rats (n = 64...

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Bibliographic Details
Main Authors: RMY Wong, U Thormann, MHV Choy, YN Chim, MCM Li, JY Wang, KS Leung, JCY Cheng, V Alt, SKH Chow, WH Cheung
Format: Article
Language:English
Published: AO Research Institute Davos 2019-05-01
Series:European Cells & Materials
Subjects:
Online Access:http://www.ecmjournal.org/papers/vol037/pdf/v037a25.pdf