Molecular targeting in acute myeloid leukemia
Abstract Acute myeloid leukemia (AML) is a heterogenous disease associated with distinct genetic and molecular abnormalities. Somatic mutations result in dysregulation of intracellular signaling pathways, epigenetics, and apoptosis of the leukemia cells. Understanding the basis for the dysregulated...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2017-08-01
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| Series: | Journal of Translational Medicine |
| Online Access: | http://link.springer.com/article/10.1186/s12967-017-1281-x |