Therapeutic Potential of Peroxisome Proliferator-Activated Receptor (PPAR) Agonists in Substance Use Disorders: A Synthesis of Preclinical and Human Evidence

Targeting peroxisome proliferator-activated receptors (PPARs) has received increasing interest as a potential strategy to treat substance use disorders due to the localization of PPARs in addiction-related brain regions and the ability of PPAR ligands to modulate dopamine neurotransmission. Robust e...

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Bibliographic Details
Main Authors: Justin Matheson, Bernard Le Foll
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/9/5/1196