Intra-individual correlations between quantitative THK-5351 PET and MRI-derived cortical volume in Alzheimer's disease differ according to disease severity and amyloid positivity.

Intra-individual correlations between quantitative THK-5351 PET and MRI-derived cortical volume in Alzheimer's disease differ according to disease severity and amyloid positivity.

PURPOSE:To assess the in vivo whole-brain relationship between uptake of [18F]THK-5351 on PET and cortical atrophy on structural MRI according to the presence and severity of Alzheimer's disease (AD). MATERIALS AND METHODS:Sixty-five participants (21 normal controls, 32 mild cognitive impairmen...

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Bibliographic Details
Main Authors: Ji Eun Park, Jessica Yun, Sang Joon Kim, Woo Hyun Shim, Jungsu S Oh, Minyoung Oh, Jee Hoon Roh, Sang Won Seo, Seung Jun Oh, Jae Seung Kim
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0226265

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https://doi.org/10.1371/journal.pone.0226265

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