Experimental long-term diabetes mellitus alters the transcriptome and biomechanical properties of the rat urinary bladder

Abstract Diabetes mellitus (DM) is the leading cause of chronic kidney disease and diabetic nephropathy is widely studied. In contrast, the pathobiology of diabetic urinary bladder disease is less understood despite dysfunctional voiding being common in DM. We hypothesised that diabetic cystopathy h...

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Bibliographic Details
Main Authors: Emad A. Hindi, Craig J. Williams, Leo A. H. Zeef, Filipa M. Lopes, Katie Newman, Martha M. M. Davey, Nigel W. Hodson, Emma N. Hilton, Jennifer L. Huang, Karen L. Price, Neil A. Roberts, David A. Long, Adrian S. Woolf, Natalie J. Gardiner
Format: Article
Language:English
Published: Nature Publishing Group 2021-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-94532-7