Estimates of statistical significance for comparison of individual positions in multiple sequence alignments
<p>Abstract</p> <p>Background</p> <p>Profile-based analysis of multiple sequence alignments (MSA) allows for accurate comparison of protein families. Here, we address the problems of detecting statistically confident dissimilarities between (1) MSA position and a set of...
Main Authors: | Sadreyev Ruslan I, Grishin Nick V |
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Format: | Article |
Language: | English |
Published: |
BMC
2004-08-01
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Series: | BMC Bioinformatics |
Online Access: | http://www.biomedcentral.com/1471-2105/5/106 |
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