Sanguinarine suppresses migration and metastasis in colorectal carcinoma associated with the inversion of EMT through the Wnt/β‐catenin signaling

Abstract Background Unresectable lung or liver organ metastases of colorectal carcinoma (CRC) remain a major obstacle in clinical therapeutics. Epithelial to mesenchymal transition (EMT), a major cause of highly frequent metastasis in tumor, can be promoted by the Wnt/β‐catenin pathway that is aberr...

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Bibliographic Details
Main Authors: Man Zhu, Zhengyan Gong, Qing Wu, Xianpeng Shi, Qi Su, Yanmin Zhang
Format: Article
Language:English
Published: Wiley 2020-03-01
Series:Clinical and Translational Medicine
Subjects:
EMT
Online Access:https://doi.org/10.1002/ctm2.1