Flaviviral Replication Complex: Coordination between RNA Synthesis and 5’-RNA Capping

Flaviviral Replication Complex: Coordination between RNA Synthesis and 5’-RNA Capping

Genome replication in flavivirus requires (—) strand RNA synthesis, (+) strand RNA synthesis, and 5’-RNA capping and methylation. To carry out viral genome replication, flavivirus assembles a replication complex, consisting of both viral and host proteins, on the cytoplasmic side of the endoplasmic...

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Bibliographic Details
Main Authors: Valerie J. Klema, Radhakrishnan Padmanabhan, Kyung H. Choi
Format: Article
Language:English
Published: MDPI AG 2015-08-01
Series:Viruses
Subjects:
viral replication complex
flavivirus
RNA-dependent RNA polymerase
RNA synthesis
5’-RNA capping
NS5
NS3
Online Access:http://www.mdpi.com/1999-4915/7/8/2837

Internet

http://www.mdpi.com/1999-4915/7/8/2837

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