Potency of vancomycin against Mycobacterium tuberculosis in the hollow fiber system model

Objectives: To determine whether an inhaled vancomycin formulation resulting in high intrapulmonary 24-h area under the concentration–time curve (AUC0–24) could be optimised for tuberculosis treatment. We also explored vancomycin synergy and antagonism with d-cycloserine and benzylpenicillin. Method...

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Bibliographic Details
Main Authors: Shashikant Srivastava, Moti Chapagain, Johanna van Zyl, Devyani Deshpande, Tawanda Gumbo
Format: Article
Language:English
Published: Elsevier 2021-03-01
Series:Journal of Global Antimicrobial Resistance
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2213716521000175