Trapping DNA Replication Origins from the Human Genome
Synthesis of chromosomal DNA is initiated from multiple origins of replication in higher eukaryotes; however, little is known about these origins’ structures. We isolated the origin-derived nascent DNAs from a human repair-deficient cell line by blocking the replication forks near the origins using...
Main Authors: | Fumio Hanaoka, Toshihiko Eki, Yasufumi Murakami |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2013-04-01
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Series: | Genes |
Subjects: | |
Online Access: | http://www.mdpi.com/2073-4425/4/2/198 |
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