Quinazolin-4(3<i>H</i>)-ones and 5,6-Dihydropyrimidin-4(3<i>H</i>)-ones from β-Aminoamides and Orthoesters
Quinazolin-4(3<i>H</i>)-ones have been prepared in one step from 2-aminobenzamides and orthoesters in the presence of acetic acid. Simple 2-aminobenzamides were easily converted to the heterocycles by refluxing in absolute ethanol with 1.5 equivalents of the orthoester and 2 equivalents...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2018-11-01
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Series: | Molecules |
Subjects: | |
Online Access: | https://www.mdpi.com/1420-3049/23/11/2925 |