Deciphering the Metabolic Pathway Difference Between Saccharopolyspora pogona and Saccharopolyspora spinosa by Comparative Proteomics and Metabonomics

Butenyl-spinosyn, a secondary metabolite produced by Saccharopolyspora pogona, exhibits strong insecticidal activity than spinosyn. However, the low synthesis capacity and unknown metabolic characteristics of butenyl-spinosyn in wild-type S. pogona limit its broad application and metabolic engineeri...

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Bibliographic Details
Main Authors: Jie Rang, Haocheng He, Shuangqin Yuan, Jianli Tang, Zhudong Liu, Ziyuan Xia, Tahir Ali Khan, Shengbiao Hu, Ziquan Yu, Yibo Hu, Yunjun Sun, Weitao Huang, Xuezhi Ding, Liqiu Xia
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-03-01
Series:Frontiers in Microbiology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2020.00396/full